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NFL Sunday Night Football Preview

October 5, 2025 by Digital Sports Desk

New England Patriots (2-2) at Buffalo Bills (4-0)
Sunday, 8:20 p.m. ET
FanDuel odds: Bills -8.5, Total 49.5

Series Rewind: Buffalo has won eight of the past 11 meetings after New England won 35 of the previous 39 matchups.

Inside Edge intel: The Bills have a streak of eight consecutive games over 100 rushing yards.

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Buffalo is one of two 4-0 teams and has racked up 133 points, second-highest in the league behind the Detroit Lions (137). The Bills are vying for their first 5-0 start since 1991, a season in which they reached the Super Bowl. Buffalo also is seeking its 15th consecutive regular-season homefield victory as the club continues to enjoy one of top atmospheres in the sport. New England receiver Stefon Diggs remembers how it works in Orchard Park after spending four seasons – making the Pro Bowl each time – with the Bills. This will be his first trip in as a visiting player since he was traded to the Houston Texans following the 2023 campaign. Diggs had six catches for 101 yards in last week’s 42-13 thumping of the Carolina Panthers. That also marked the first time New England reached the 40-point mark since 2021. Second-year quarterback Drake Maye is developing well and has completed 74 percent of his passes for 988 yards, seven touchdown and two interceptions. He also has rushed for two scores. Reigning NFL MVP Josh Allen of the Bills has thrown for 964 yards, seven touchdowns and one interception while also rushing for three scores. James Cook is the NFL’s second-leading rusher with 401 yards and has a league-best five rushing touchdowns. New England allowed an opening-drive touchdown in three of its first four games.

Filed Under: Boston Sports, NFL, Patriots Tagged With: Buffalo Bills, New England Patriots, NFL

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