Carolina Panthers (3-5) at New Orleans Saints (3-5)
Sunday, 1 p.m. ET
FanDuel odds: Saints -1.5, total 48.5
Series Rewind: The Saints have won five of the past six meetings and beat the Panthers 20-17 last December to remain in a tight NFC South race eventually claimed by Carolina on Week 18 tiebreakers.
Carolina has a top-five passing offense (261.1 yards per game, 4th in the NFL) and Bryce Young is on pace to approach a 4,000-yard, 30-TD season. He threw three touchdown passes and completed 28 of 39 for 276 yards last week, his ninth consecutive game with a TD pass. Carolina is getting more consistent production from the tight end position this season. Darren Waller (eight receptions for 90 yards last week) and wide receiver Tetairoa McMillan give Young a super-sized tandem to target downfield, and massive matchup problems for most safeties and cornerbacks. New Orleans is counting on its pass rush to make Young uncomfortable. He’s been sacked nine total times in the past two games. New Orleans won a home game for the first time this season last week, stopping a two-point conversion on the final play to beat the Cleveland Browns 23-22 in overtime. Quarterback Tyler Shough and wide receiver Chris Olave have played well in this series. Shough has a 110-plus passer rating in two career games against the Panthers and Olave has at least five receptions, 85 yards and a touchdown in the past two meetings.
Minnesota Vikings (6-2) at Green Bay Packers (6-3)
Sunday, 1 p.m. ET
FanDuel odds: Packers -3, total 42.5
Series Rewind: The Vikings opened the season with a 39-22 defeat of the Packers in Minneapolis. Minnesota has won five of the last seven meetings in the NFC North rivalry, including victories at Lambeau Field in 2023 and 2024.
Minnesota ranks first in the NFL in scoring defense (14.5), is tied for first in sacks (29) and ranks second in total defense (280.0) and faces a Green Bay offense that ranks second in passing (279.7) but dead last in rushing (68.2). The Vikings brought back Kirk Cousins in a trade with the Raiders and the 38-year-old veteran is expected to start Sunday. He is 6-4-1 in his career against the Packers with 23 touchdown passes and eight interceptions. The last time he suited up for the Vikings was at Lambeau Field, and he exited the Week 8 game in 2023 with a ruptured Achilles. Green Bay counterpart Jordan Love enters Week 10 leading the NFL in passing yards (2,618) and the NFC in touchdown passes (19). Matthew Golden and Christian Watson are the first pair of wide receivers since 2019 with at least 45 catches, 750 yards and five TDs apiece in the first nine games of a season. Former Packers running back Aaron Jones already has two 100-yard road games this season for the Vikings (at New Orleans and at Chicago). In Minnesota’s Week 1 win, Justin Jefferson caught eight passes for 92 yards and two scores.
Miami Dolphins (1-7) at Indianapolis Colts (2-7)
Sunday, 1 p.m. ET
FanDuel odds: Colts -3.5, total 38.5
Series Rewind: The Colts are going for a fourth consecutive win over the Dolphins, who lost on the same field to open the 2025 season (33-8).
Miami pushes Kyle McCord to center stage to make his first career start at quarterback and the Colts are attempting to find their footing following an active trade deadline in which wide receivers Josh Downs and Keenan Allen, defensive tackle DeForest Buckner and left guard Quenton Nelson were shipped out. Colts running back Jonathan Taylor stayed put and stirs the offense for Indianapolis, especially with few established options to run routes for quarterback Daniel Jones. Taylor’s matchup with Dolphins linebacker Jordyn Brooks (14 tackles in the 2025 meeting) should be intriguing. How Miami moves the ball won’t be quite as clear. McCord likely is to look to rookie wide receiver Caleb Douglas, who is averaging 15.8 yards per reception, and running back Ollie Gordon II. Gordon has consecutive road games with at least 100 yards from scrimmage.
Houston Texans (3-5) at Cleveland Browns (5-4)
Sunday, 1 p.m. ET
FanDuel odds: Texans -4.5, total 40.5
Series Rewind: Houston ended a four-game losing streak against the Browns the last time these teams met, winning 45-14 in a wild-card playoff game in January 2024. That restored the Texans’ lead in the all-time series, 8-7.
The last time the Browns started a season 4-0 at home was 1963, one year before they captured their most recent NFL championship. Deshaun Watson will attempt to maintain Cleveland’s perfect home record Sunday when he returns to the starting lineup for the Browns against his former team. Shedeur Sanders got the start last week while Watson was in concussion protocol, throwing for 297 yards and two touchdowns in a 23-22 overtime loss to the Saints. Cleveland trails the Steelers (6-2) and Bengals (6-2) by 1 1/2 games in the AFC North. Those teams face off Sunday night, giving Watson a chance to help the Browns gain ground in the division race. The Texans have a lot more ground to make up in their division, three games back of Jacksonville. Houston is following a path similar to the one it took to reach the divisional playoffs last season, when it started 0-3 before earning a wild-card berth. The Texans were 0-4 this year before notching their first victory of the season Oct. 11 at Tennessee, and they now have three wins away from home in the past four games. Houston QB C.J. Stroud passed for 384 yards and five touchdowns in a 44-22 road victory over the Los Angeles Chargers last week. The Texans’ point total tied for the most in franchise history in a road game.
Buffalo Bills (7-1) at New York Jets (2-7)
Sunday, 1 p.m. ET
FanDuel: Bills -7.5, total: 50.5
Series Rewind: Buffalo has defeated its AFC East rivals five straight times by an average of 20.4 and have prevailed in 10 of the last 12 meetings. The Bills outscored New York 65-18 in last season’s two matchups. The Jets have scored 14 or fewer points in four of the last five matchups.
Buffalo owns a four-game winning streak and has best record in the AFC as it enters the true midseason (Game 9) clash. The Bills allowed just 16 points over the last two games and totally shut down the Minnesota Vikings in Monday’s 23-6 road victory. Buffalo gave up just 178 yards and nine first downs while forcing three turnovers. And the defense landed another stellar player the following day when the Bills obtained safety Amani Hooker from the Tennessee Titans. The eighth-year veteran shares the NFL lead with five interceptions. Buffalo quarterback Josh Allen passed for 234 yards against Minnesota and his lone 300-yard outing (334) came in the season-opening victory over the Houston Texans. James Cook III rushed for 107 yards against the Vikings. Cook ranks fifth in the NFL with 814 rushing yards. The Jets have lost four consecutive games after being routed 35-12 last week by the host Kansas City Chiefs. New York trailed 14-12 at halftime before being dominated in the second half. The 12 points matched a season low and New York had just 229 yards and quarterback Geno Smith was sacked five times. The Jets are 5-21 in 1 1/2 seasons under Glenn, and speculation about his future is heating up. Glenn was a three-time Pro Bowl cornerback who intercepted 41 passes during his 15-year playing career, but his Jets haven’t had the same zeal for picks. Safety Minkah Fitzpatrick’s interception in Week 4 of this season remains New York’s lone pick during Glenn’s 26 games at the helm. No. 2 overall pick David Bailey has displayed a knack for forcing fumbles. The edge rusher shares the NFL lead with five forced fumbles and also is tied for fourth with 7.5 sacks.