Buffalo Bills (10-4) at Cleveland Browns (3-11)
Sunday, 1 p.m. ET
FanDuel odds: Bills -10.5, Total 41.5
Series Rewind: The Browns have the 13-10 edge all-time (counting playoffs), but Buffalo has won three of the past four and five of seven in the series. However, it’s been since 2012 that the Bills won in Cleveland, falling short there in 2013 and 2019.
The Bills have at least 10 wins for the seventh straight season, the longest streak in franchise history. Next in their sights is seven straight years with a playoff trip; the Bills need one more win along with a loss by either Houston or Indianapolis in order to punch their ticket. Reigning NFL MVP Josh Allen leads the league’s top rushing offense (158.5 yards per game) and third-best scoring offense (29.4 ppg), as he has totaled 37 touchdowns to this point, 25 passing and 12 rushing. Dawson Knox had two touchdown receptions in last week’s crucial win over AFC East leader New England, and he could see additional playing time if fellow tight end Dalton Kincaid is hindered by his knee injury. Browns rookie QB Shedeur Sanders will face a tall task in challenging the Bills, who boast the second-stingiest passing defense (169.5 yards per game) in the NFL. Sanders’ fifth career game and fourth start was his worst so far, with 177 yards and three picks in last week’s 31-3 loss at Chicago. The Browns are not playoff-bound, but one storyline worth watching is Myles Garrett’s shot at breaking the single-season sacks record. He collected 1.5 sacks last week to boost his season total to 21.5, one shy of the record shared by Michael Strahan (in 2001) and T.J. Watt (in 2021).
Tampa Bay Buccaneers (7-7) at Carolina Panthers (7-7)
Sunday, 1 p.m. ET
FanDuel odds: Buccaneers -3, Total 48.5
Series Rewind: The Buccaneers walloped Carolina 48-14 last December and swept the 2024 season series to run their dominance in the series to nine wins in the past 10 games.
Since the start of the 2021 season, the Buccaneers can claim ownership of the South, holding at least a share of the division lead for 73 of the 87 weeks with four consecutive division titles. Carolina last won the division in 2015 but the Panthers share first place in the NFC South, matching Tampa Bay’s current 7-7 record with three weeks — and two games against the Buccaneers — left in the regular season. “We’re in the same position we’ve been in the past two or three years,” Buccaneers coach Todd Bowles said of a tight race. “We have an opportunity. We still have everything right in front of us. … We’re playing meaningful games in December.” The Panthers might be early arrivals to the postseason conversation under second-year coach Dave Canales. Wins over NFC contenders — most recently beating the Los Angeles Rams, 31-28, on Nov. 30 — has helped shift the narrative. Canales and the Panthers are well aware of the final step necessary to realize a postseason goal: beat the division champs. The Buccaneers have won five consecutive meetings and during their 9-1 string over the past five years, Tampa outscored Carolina by 124 points (287-163). The Buccaneers have won only once since October, so their 1-5 record coming down the stretch has been troublesome. They’ve lost to NFC South rivals New Orleans and Atlanta in their past two games. Bucs quarterback Baker Mayfield, a former Panther, was coached by Canales in Tampa before the Panthers hired him away in 2024. Mayfield should have a nice selection of weapons to work with after last week’s return of wide receiver Mike Evans. Coming back from a collarbone injury, Evans hauled in six catches for 132 yards in the Atlanta game and already had the Panthers’ full attention.
Los Angeles Chargers (10-4) at Dallas Cowboys (6-7-1)
Sunday, 1 p.m. ET
FanDuel odds: Cowboys -1.5, Total 49.5
Series Rewind: The Chargers have won their past three road games in the series. Their last road loss against Dallas came in 1990 when the Cowboys played in Irving.
The Cowboys must win their three remaining regular-season games and have the NFC East-leading Philadelphia Eagles lose all three of theirs to avoid missing the playoffs for the second straight season. The outlook isn’t looking good after Dallas allowed 78 total points while losing back-to-back games to the Detroit Lions and Minnesota Vikings. Dak Prescott leads the NFL with 3,931 passing yards while closing in on his fourth career 4,000-yard campaign. Tony Romo is the only Cowboys quarterback currently with four such seasons. Prescott ranks third with 26 touchdown passes, and he has been intercepted 10 times. Wideout CeeDee Lamb is 24 yards shy of his fifth straight 1,000-yard season. The Chargers are red-hot with six wins in their past seven games. Los Angeles can clinch a playoff spot with a win over the Cowboys along with some help from either the Las Vegas Raiders (against the Houston Texans) or San Francisco 49ers (vs. the Indianapolis Colts). The Chargers allowed just 239 yards in last week’s 16-13 road win over the Kansas City Chiefs. It marked the third straight game and sixth in the past seven that the Chargers gave up 20 or fewer points. Justin Herbert (3,191 yards) will play for the third straight week after undergoing left hand surgery.
Kansas City Chiefs (6-8) at Tennessee Titans (2-12)
Sunday, 1 p.m. ET
FanDuel odds: Chiefs -3, Total 37.5
Series Rewind: Andy Reid is 3-9 all-time against the Titans. Tennessee interim head coach Mike McCoy is 2-6 all-time against the Chiefs.
Chiefs coach Andy Reid isn’t in a tinsel-tossing mood days after losing Patrick Mahomes to a season-ending knee injury last Sunday. While Mahomes gets busy attacking post-surgery rehabilitation with a goal of getting on the field in September, the Titans are eager for any advantage to help further rookie QB Cam Ward’s development. Tennessee has been outscored by a league-worst 169 points with 24 fewer touchdowns than its opponents. The Chiefs have a three-game losing streak and lug the emotional letdown of losing Mahomes and what was left of faint playoff hopes last week in a 16-13 heartbreaker to the Chargers. Gardner Minshew takes the reins for the Chiefs with questions around the formation due to injuries at the wide receiver position. He went to TE Travis Kelce consistently in his cameo subbing for Mahomes last week. Kelce is 203 yards shy of 1,000 yards for the season and 13 receptions away from hitting 80 for the 10th year in a row. The Titans have their highest two-game point total of the season — 55. Kansas City put up 23 total points the past two weeks and was held under 275 total yards by the Chargers and Texans.
Minnesota Vikings (6-8) at New York Giants (2-12)
Sunday, 1 p.m. ET
FanDuel odds: Vikings -2.5, Total 43.5
Series Rewind: What a difference a year makes. Minnesota opened the 2024 season with a 28-6 win against the Giants at MetLife Stadium when the starting QBs were Sam Darnold (Vikings) and Daniel Jones (New York).
A couple of 22-year-old quarterbacks go head-to-head as Minnesota’s J.J. McCarthy makes his ninth NFL start and New York’s Jaxson Dart makes his 10th. The Vikings have followed up a four-game losing streak with two straight wins against the NFC East, with McCarthy throwing five touchdowns and just one interception in victories against the Commanders and Cowboys. The Giants have lost eight in a row and are 0-2 against the NFC North with losses to the Bears and Packers. Dart leads all rookie QBs in TD passes (13) and ranks second in passing yards (1,802). Vikings star Justin Jefferson hasn’t caught a touchdown pass since Week 9 and hasn’t topped 100 yards since Week 5. New York first-round pick LB Abdul Carter is coming off a monster game vs. Washington and is looking for his third straight game with a sack. Giants LB Brian Burns is second in the NFL with 13 sacks. McCarthy has been sacked 24 times in eight games.
Cincinnati Bengals (4-10) at Miami Dolphins (6-8)
Sunday, 1 p.m. ET
FanDuel odds: Bengals -4.5, Total 47.5
Series Rewind: The Dolphins lead the all-time series 18-8, but the Bengals won the most recent game in the series (27-15 in 2022) and have won three of the past five over Miami.
While Cincinnati and Miami were both eliminated from playoff contention with their losses last week, they’re approaching that news in vastly different ways. The Dolphins are benching starting QB Tua Tagavailoa, who has a league-leading 15 interceptions and had just 65 passing yards through three quarters of Monday’s 28-15 loss at Pittsburgh. Quinn Ewers, a seventh-round pick in April’s draft, will make his first career start against the Bengals. He came off the bench to complete 5 of 8 passes for 53 yards in his first career appearance Oct. 19 at Cleveland. He’ll likely be helped by breakout running back De’Von Achane, who has 105-plus scrimmage yards in six straight games and a touchdown in 10 of his last 11 home games. The Bengals, on the other hand, are sticking with quarterback Joe Burrow despite not having any remaining postseason stakes. Cincinnati was shut out for the first time in a Burrow start last week, falling 24-0 at home to the Ravens. In his first three starts back from a toe injury that sidelined him for nine games, Burrow has 770 passing yards, six touchdowns and four interceptions. With 132 yards last week, receiver Ja’Marr Chase became just the second player in NFL history (along with Randy Moss) to amass 6,500 receiving yards and 50 touchdown catches in his first five seasons.
New York Jets (3-11) at New Orleans Saints (4-10)
Sunday, 1 p.m. ET
FanDuel odds: Saints -5.5, Total 40.5
Series Rewind: These teams have faced off just five times in the past 20 years. New Orleans has won four of those games, including the past two, to claim an 8-6 lead in the all-time series.
While both New York and New Orleans are nearing the end of underwhelming seasons, they probably feel a bit differently about the rookie quarterbacks they’ll start in this week’s matchup. Saints second-round pick Tyler Shough enters coming off back-to-back wins over division opponents, the team’s first multiple-game winning streak of the season. After rushing for 55 yards and two scores Dec. 7 vs. Tampa Bay, Shough completed a career-high 75% of his passes for 272 yards and a touchdown in Sunday’s 20-17 win over Carolina. New Orleans is 3-4 when Shough starts after it was 1-6 with Spencer Rattler at the helm. With 52 more receiving yards, Saints running back Alvin Kamara would become the fifth player in NFL history with 5,000 rushing and receiving yards in his career. Jets rookie QB Brady Cook has been forced into action due to injuries to Tyrod Taylor and Justin Fields. He had a touchdown and three interceptions in his first career start last week vs. Jacksonville and has thrown 339 yards and five interceptions in his first two games. Jets coach Aaron Glenn fired defensive coordinator Steve Wilks this week after the defense allowed 48 points in the loss to the Jaguars. New York is 30th in scoring defense (28.4 points per game) and last in takeaways (three), with no interceptions this season.